Renovascular Hypertension and Ischemic Nephropathy

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Renovascular hypertension and ischemic nephropathy.

Renovascular disease remains among the most prevalent and important causes of secondary hypertension and renal dysfunction. Many lesions reduce perfusion pressure including fibromuscular diseases and renal infarction, but most are caused by atherosclerotic disease. Epidemiologic studies establish a strong association between atherosclerotic renal-artery stenosis (ARAS) and cardiovascular risk. ...

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The major issues in approaching patients with renal artery stenosis relate to the role of renal artery stenosis in the management of hypertension, ie, “renovascular hypertension,” and to the potential for vascular compromise of renal function, ie, “ischemic nephropathy.” Ever since the original Goldblatt experiment in 1934, wherein experimental hypertension was produced by renal artery clamping...

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ژورنال

عنوان ژورنال: Circulation

سال: 2005

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.104.492348